BioTE testosterone pellet therapy, hormone optimization, full panels
Ordered by Dr. Maya J. Halliburton at Gordon Crofoot MD PA. Results expected by Monday, March 16, 2026.
| Test | Code | ICD-10 Dx | Interpretation |
|---|---|---|---|
| Prot+CreatU (Random) | 003129 | N39.8 | Urine protein & creatinine ratio — kidney function screening |
| Testosterone, Serum | 004226 | E34.9 | Endocrine monitoring — testosterone level assessment |
| CBC With Differential/Platelet | 005009 | E34.9 | Complete blood count — overall blood health |
| HbA1c with eAG Estimation | 102525 | E11.8 | 3-month blood sugar average — TYPE 2 DIABETES |
| Lipid Panel | 303756 | Z13.220 | Cholesterol screening — cardiovascular risk assessment |
| Comprehensive Metabolic Panel (14) | 322000 | E34.9 | Organ function baseline — liver, kidney, electrolytes, glucose |
When results arrive, key numbers to compare against historical trends: HbA1c (target <6.5%, ideal <5.7%), Fasting Glucose (target <100), Testosterone (on/off TRT context), HDL (target >40), LDL (target <100).
Primary concern: Type 2 Diabetes confirmed December 2025. Currently on Metformin + Signos CGM. Goal: regain insulin sensitivity.
| Date | HbA1c | Status | Provider | Trend |
|---|---|---|---|---|
| Feb 2019 | 5.5% | NORMAL | NBH — Dr. Szelei-Stevens | — |
| Dec 2018 | 6.0% | PREDIABETIC | NBH — Dr. Szelei-Stevens | ↑ +0.5 |
| Aug 2021 | 6.1% | PREDIABETIC | NBH — Dr. Jackson | ↑ +0.1 |
| May 2022 | 6.2% | DIABETIC RANGE | NBH — Dr. Jackson | ↑ +0.1 |
| Oct 2023 | 6.2% | DIABETIC RANGE | NBH/CPL — Dr. Jackson | → 0.0 |
| Mar 2026 | Pending | ORDERED | Crofoot — Dr. Halliburton | — |
| Date | Glucose (mg/dL) | Ref: 70–99 | Trend |
|---|---|---|---|
| Dec 2018 | 94 | NORMAL | — |
| Aug 2021 | 99 | BORDERLINE | ↑ +5 |
| May 2022 | 111 | HIGH | ↑ +12 |
| Oct 2023 | 145 | HIGH | ↑ +34 |
| Mar 2026 | Pending (CMP) | ORDERED | — |
| Date | Insulin (UIU/mL) | Ref: 2–21 | HOMA-IR Est. | Trend |
|---|---|---|---|---|
| Feb 2019 | 8 | NORMAL | ~1.0 (optimal) | — |
| Aug 2021 | 12 | RISING | ~2.9 (borderline) | ↑ +4 |
| May 2022 | 13 | RISING | ~3.6 (resistant) | ↑ +1 |
| Dec 2018 | 16 | ELEVATED | ~3.7 (resistant) | ↑ +3 |
| Oct 2023 | 17 | HIGH-NORMAL | ~6.1 (resistant) | ↑ +1 |
Insulin has more than doubled from 8 (2019) to 17 (2023) while remaining within “normal” lab range. This is the classic Type 2 progression: the body produces more insulin to compensate for resistance, glucose still rises. HOMA-IR >2.5 indicates insulin resistance. By Oct 2023, estimated HOMA-IR was ~6.1 — well into resistant territory.
Current interventions: Metformin (daily), Signos CGM (switched from Stelo Jan 2026), health coach Jamie exploring GLP-1/peptide options.
History of BioTE testosterone pellet therapy through Natural Bio Health-Houston. Levels fluctuate dramatically based on TRT status.
| Date | Testosterone (ng/dL) | Ref: 300–890 | TRT Status | Provider |
|---|---|---|---|---|
| Jul 2017 | 1,237 | HIGH (on TRT) | Post-Pellet Profile | NBH — Dr. Szelei-Stevens |
| Nov 2017 | 642 | NORMAL | Follow-up (waning) | NBH — Dr. Szelei-Stevens |
| Dec 2018 | 656 | NORMAL | Off / Between cycles | NBH — Dr. Szelei-Stevens |
| Feb 2019 | 1,550 | HIGH (on TRT) | On pellets | NBH — Dr. Szelei-Stevens |
| Jul 2019 | 916 | SLIGHTLY HIGH | On pellets (waning) | NBH — Dr. Szelei-Stevens |
| Aug 2021 | 447 | NORMAL | Off TRT | NBH — Dr. Jackson |
| May 2022 | 1,372 | HIGH (on TRT) | On pellets | NBH — Dr. Jackson |
| Oct 2023 | 1,357 | HIGH (on TRT) | On pellets | NBH/CPL — Dr. Jackson |
| Mar 2026 | Pending | ORDERED | Unknown | Crofoot — Dr. Halliburton |
| Date | Free T (pg/mL) | Ref: 47–244 | SHBG (nmol/L) | Ref: 19.3–76.4 |
|---|---|---|---|---|
| Jul 2017 | 21.3* | diff ref range | 60.3 | NORMAL |
| Nov 2017 | 13.4* | diff ref range | 35.9 | NORMAL |
| Dec 2018 | 78.9 | NORMAL | 76.1 | BORDERLINE |
| Feb 2019 | 224.3 | NORMAL | 81.2 | HIGH |
| Jul 2019 | 134.9 | NORMAL | 65.3 | NORMAL |
| Aug 2021 | 76.1 | NORMAL | — | — |
| May 2022 | 279.2 | HIGH | 50.6 | NORMAL |
| Oct 2023 | 289.4 | HIGH | 47.0 | NORMAL |
| Date | FSH (IU/L) | LH (IU/L) | DHEA-S (ug/dL) | Estradiol (pg/mL) |
|---|---|---|---|---|
| Feb 2019 | — | — | 83 | — |
| May 2022 | <0.3 L | — | — | — |
| Oct 2023 | <0.3 L | <0.3 L | 323 H | 59.1 |
FSH and LH are fully suppressed (<0.3) when on testosterone therapy — this is expected. The body’s natural production shuts down when exogenous testosterone is present. DHEA-S at 323 (high) in Oct 2023 may indicate adrenal overcompensation. Hematocrit elevation (51.3%) is a known TRT side effect requiring monitoring.
| Date | Total Chol | LDL | HDL | Triglyc | Risk Ratio |
|---|---|---|---|---|---|
| Dec 2018 | 174 | 117 H | 37 L | 98 | 3.17 |
| Aug 2021 | 236 H | 170 H | 42 | 115 | — |
| May 2022 | 184 | 136 H | 33 L | 61 | — |
| Oct 2023 | 182 | 133 H | 30 L | 89 | — |
| Mar 2026 | Pending | Pending | Pending | Pending | — |
HDL has dropped steadily: 42 → 37 → 33 → 30. An HDL below 40 mg/dL in men is considered a major cardiovascular risk factor. At 30, this is seriously low. LDL remains consistently elevated above 100. Combined with Type 2 diabetes, this creates a compounded cardiovascular risk profile.
| Date | hsCRP (mg/L) | Risk Level | Homocysteine (umol/L) | Ref: <12 |
|---|---|---|---|---|
| Dec 2018 | 1.3 | AVERAGE | 13 H | ELEVATED |
| Feb 2019 | — | — | 12 H | BORDERLINE |
| Jul 2019 | — | — | 14 H | HIGH |
| Aug 2021 | 0.9 | LOW | 10 | NORMAL |
| May 2022 | — | — | 13 H | ELEVATED |
| Oct 2023 | 1.2 | AVERAGE | 10 | NORMAL |
| Date | Vitamin D (ng/mL) | Status | Trend |
|---|---|---|---|
| Feb 2019 | 18 | INSUFFICIENT (<20) | — |
| Jul 2019 | 24 | SUBOPTIMAL (20–29) | ↑ +6 |
| Aug 2021 | 28 | SUBOPTIMAL (20–29) | ↑ +4 |
| May 2022 | 62 | OPTIMAL (30–100) | ↑ +34 |
| Oct 2023 | 27 | SUBOPTIMAL (20–29) | ↓ -35 |
Vitamin D reached optimal levels (62 ng/mL) in May 2022, likely with active supplementation. By Oct 2023 it crashed back to 27 — suggesting supplementation was discontinued. Vitamin D deficiency worsens insulin resistance, immune function, and bone density. Recommendation: Resume 5,000 IU daily D3 with K2.
| Date | Ferritin (ng/mL) | ALT (U/L) | Hematocrit (%) | PSA (ng/mL) |
|---|---|---|---|---|
| Dec 2018 | 369 | 48 | 45.9 | 0.83 |
| Aug 2021 | 511 H | 62 H | — | — |
| May 2022 | 372 | 45 | — | — |
| Oct 2023 | 241 | 48 | 51.3 H | 0.93 |
Ferritin normalizing trend (511 → 241). ALT fluctuating near upper limit (liver function). Hematocrit elevated on TRT — requires monitoring for polycythemia risk. PSA stable and low (<1.0).
| Marker | Ref Range | Jul 17 | Nov 17 | Dec 18 | Feb 19 | Jul 19 | Aug 21 | May 22 | Oct 23 | Mar 26 |
|---|---|---|---|---|---|---|---|---|---|---|
| HbA1c (%) | 4.2–5.6 | — | — | 6.0 | 5.5 | — | 6.1 | 6.2 | 6.2 | ? |
| Glucose (mg/dL) | 70–99 | — | — | 94 | — | — | 99 | 111 | 145 | ? |
| Insulin (UIU/mL) | 2–21 | — | — | 16 | 8 | — | 12 | 13 | 17 | — |
| Testosterone (ng/dL) | 300–890 | 1237 | 642 | 656 | 1550 | 916 | 447 | 1372 | 1357 | ? |
| Free T (pg/mL) | 47–244 | 21.3* | 13.4* | 78.9 | 224.3 | 134.9 | 76.1 | 279.2 | 289.4 | — |
| Vitamin D (ng/mL) | 30–100 | — | — | — | 18 | 24 | 28 | 62 | 27 | — |
| Total Cholesterol | <200 | — | — | 174 | — | — | 236 | 184 | 182 | ? |
| LDL (mg/dL) | <100 | — | — | 117 | — | — | 170 | 136 | 133 | ? |
| HDL (mg/dL) | >39 | — | — | 37 | — | — | 42 | 33 | 30 | ? |
| Triglycerides | <150 | — | — | 98 | — | — | 115 | 61 | 89 | ? |
| Homocysteine | <12 | — | — | 13 | 12 | 14 | 10 | 13 | 10 | — |
| hsCRP (mg/L) | <1.0 low | — | — | 1.3 | — | — | 0.9 | — | 1.2 | — |
| Ferritin (ng/mL) | 30–400 | — | — | 369 | — | — | 511 | 372 | 241 | — |
| ALT (U/L) | 5–50 | — | — | 48 | — | — | 62 | 45 | 48 | — |
| Hematocrit (%) | 37–49/51 | 45.5 | — | 45.9 | — | 49.6 | — | — | 51.3 | ? |
* Jul/Nov 2017 Free T used different reference range (4.8–25.7 ng/dL). Red = above range. Blue = below range. Green = normal. Purple = pending Mar 2026 results.
The data tells a clear story: insulin went from 8 (2019, optimal) to 17 (2023, resistant). Meanwhile HbA1c crept from 5.5% to 6.2% and glucose from 94 to 145. This is textbook progressive insulin resistance leading to Type 2 diabetes.
HDL has declined from 42 to 30 over 5 years. Below 40 is a recognized independent risk factor. Combined with LDL >130 and diabetes, this significantly elevates heart disease risk.
Vitamin D reached 62 (optimal) in May 2022 with active supplementation, then crashed to 27 by Oct 2023. Vitamin D deficiency worsens insulin resistance and cardiovascular risk — both primary concerns.
Testosterone therapy drives hematocrit up (51.3% in Oct 2023, at upper limit). Values >54% increase clot risk. FSH/LH are fully suppressed — natural production is offline. If TRT is continued, regular CBC monitoring is essential.
| Item | Type | Purpose | Since |
|---|---|---|---|
| Metformin | Medication (daily) | Insulin sensitizer — first-line T2D | ~2025 |
| Signos CGM | Device (continuous) | Real-time glucose monitoring | Jan 2026 (switched from Stelo/Dexcom) |
| BioTE Testosterone Pellets | Hormone therapy | Testosterone replacement | ~2017 (intermittent) |
| GLP-1 Agonist | Under discussion | Insulin resistance reversal | Pending — per Jamie’s recommendation |
This section will be updated when results arrive. Key comparisons to make:
| Marker | Oct 2023 | Target | Mar 2026 | Direction Needed |
|---|---|---|---|---|
| HbA1c | 6.2% | <6.0% | — | Needs to drop (Metformin + diet impact) |
| Glucose | 145 | <100 | — | Needs significant drop |
| HDL | 30 | >40 | — | Needs to rise |
| LDL | 133 | <100 | — | Needs to drop |
| Testosterone | 1,357 | 300–890 | — | Context-dependent (TRT status) |
| Hematocrit | 51.3% | <50% | — | Watch for polycythemia |
Note: 2.5 year gap since last NBH labs (Oct 2023). This is the longest gap in the dataset. Metformin, CGM, and lifestyle changes since then should show in these results.